Gene description for GZMB
Gene name granzyme B
Gene symbol GZMB
Other names/aliases C11
CCPI
CGL-1
CGL1
CSP-B
CSPB
CTLA1
CTSGL1
HLP
SECT
Species Homo sapiens
 Experiment description of studies that identified GZMB in Prostate cancer cells

1
Experiment ID634
Identified moleculeprotein
Extracellular vesicle typeExtracellular vesicles
MISEVEVs
Identification method Mass spectrometry [LTQ]
PubMed ID 27894104   
OrganismHomo sapiens
Experiment descriptionProteomic profiling of NCI-60 extracellular vesicles uncovers common protein cargo and cancer type-specific biomarkers.
AuthorsHurwitz SN, Rider MA, Bundy JL, Liu X, Singh RK, Meckes DG Jr.
Journal name Oncotarget
Publication year2016
SampleProstate cancer cells
Sample namePC-3
Isolation/purification methodsDifferential centrifugation
Polymer-based precipitation
Ultracentrifugation
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyMass spectrometry [LTQ]
EV-TRACK -

2
Experiment ID2293
Identified moleculeProtein
Extracellular vesicle typeExtracellular vesicles
MISEVSmall EVs
Identification method ELISA
PubMed ID 30891164   
OrganismHomo sapiens
Experiment descriptionExtracellular vesicles derived from natural killer cells use multiple cytotoxic proteins and killing mechanisms to target cancer cells
AuthorsWu CH, Li J, Li L, Sun J, Fabbri M, Wayne AS, Seeger RC, Jong AY.
Journal name J Extracell Vesicles
Publication year2019
SampleProstate cancer cells
Sample nameDU145
Isolation/purification methodsPolyethylene glycol-based precipitation
Centrifugation
Dialysis
Flotation density-
Molecules identified in the studyProtein
Methods used in the studyELISA
EV-TRACK -

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